Table 5.
Multivariable logistic regression analysis of predictors for AS accumulation in the GI tract in patients with PD
| Predictor | Univariable | Model 1 | Model 2 | Model 3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B | Exp (B) (95% CI) | p-value | B | Exp (B) (95% CI) | p-value | B | Exp (B) (95% CI) | p-value | B | Exp (B) (95% CI) | p-value | |
| Duration from symptom onset to surgery | 0.144 | 1.155 (1.038, 1.284) | 0.008 | 0.146 | 1.157 (1.038, 1.289) | 0.008 | 0.125 | 1.133 (1.012, 1.269) | 0.031 | 0.129 | 1.138 (1.003, 1.292) | 0.045 |
| Surgical site (UGI vs. LGI) | 1.044 | 2.840 (1.095, 7.366) | 0.032 | 1.091 | 2.976 (1.096, 8.084) | 0.032 | 1.065 | 2.899 (1.042, 8.070) | 0.042 | 1.065 | 2.899 (1.042, 8.070) | 0.042 |
| Duration from symptom onset to diagnosis | 0.373 | 1.452 (0.981, 2.148) | 0.062 | 0.246 | 1.279 (0.869, 1.882) | 0.212 | 0.246 | 1.279 (0.869, 1.882) | 0.212 | |||
| Age at surgery | 0.036 | 1.036 (0.968, 1.110) | 0.306 | 0.005 | 1.005 (0.932, 1.083) | 0.906 | ||||||
| Age at symptom onset | −0.025 | 0.975 (0.919, 1.035) | 0.406 | 0.005 | 1.005 (0.932, 1.083) | 0.906 | ||||||
| Sex (Male vs. Female) | −0.474 | 0.622 (0.246, 1.575) | 0.317 | 0.177 | 1.194 (0.425, 3.352) | 0.737 | 0.177 | 1.194 (0.425, 3.352) | 0.737 | |||
| Nagelkerke R2 | 0.183 | 0.216 | 0.216 | |||||||||
| Cox & Snell R2 | 0.123 | 0.146 | 0.146 | |||||||||
| −2 Log likelihood | 95.799 | 93.285 | 93.285 | |||||||||
| Chi-square | 12.741 | 15.255 | 15.255 | |||||||||
| Chi-square p-value | 0.002 | 0.009 | 0.009 | |||||||||
PD Parkinson’s disease, AS alpha-synuclein, CI confidence interval, GI gastrointestinal, UGI upper GI tract, LGI lower GI tract.