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. 2024 Apr 8;25(4):261–297. doi: 10.2174/0113892029273121240401060228

Table 13.

Top 20 of 50 Selective KEGG pathways in the brain.

No ID Description Significant Annotated p-value q-value
1 ko04721 Synaptic vesicle cycle 33/874 43/5400 0.000 0.000
2 ko04724 Glutamatergic synapse 39/874 67/5400 0.000 0.000
3 ko04723 Retrograde endocannabinoid signaling 38/874 65/5400 0.000 0.000
4 ko04080* Neuroactive ligand-receptor interaction 77/874 218/5400 0.000 0.000
5 ko04727 GABAergic synapse 31/874 55/5400 0.000 0.000
6 ko04725 Cholinergic synapse 31/874 65/5400 0.000 0.000
7 ko04728 Dopaminergic synapse 36/874 87/5400 0.000 0.000
8 ko04713 Circadian entrainment 28/874 59/5400 0.000 0.000
9 ko04360* Axon guidance 44/874 118/5400 0.000 0.000
10 ko04020* Calcium signaling pathway 39/874 105/5400 0.000 0.000
11 ko04726 Serotonergic synapse 30/874 73/5400 0.000 0.000
12 ko04911 Insulin secretion 24/874 53/5400 0.000 0.000
13 ko04921 Oxytocin signaling pathway 36/874 99/5400 0.000 0.000
14 ko04024 cAMP signaling pathway 40/874 117/5400 0.000 0.000
15 ko04540* Gap junction 26/874 63/5400 0.000 0.000
16 ko04072* Phospholipase D signaling pathway 32/874 90/5400 0.000 0.000
17 ko04261* Adrenergic signaling in cardiomyocytes 32/874 92/5400 0.000 0.000
18 ko04114 Oocyte meiosis 29/874 80/5400 0.000 0.000
19 ko04070 Phosphatidylinositol signaling system 23/874 58/5400 0.000 0.000
20 ko04915 Estrogen signaling pathway 23/874 60/5400 0.000 0.000

Note: * also significantly expressed in other organs. Sorted by q-value.