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. 2024 Apr 8;25(4):261–297. doi: 10.2174/0113892029273121240401060228

Table 16.

Top 20 of 21 Selective KEGG pathways in the heart.

No. ID Description Significant Annotated p-value q-value
1 ko00190 Oxidative phosphorylation 74/331 108/5400 1.14E-66 2.01E-64
2 ko04260 Cardiac muscle contraction 27/331 54/5400 2.79E-19 2.46E-17
3 ko00020 Citrate cycle (TCA cycle) 16/331 24/5400 1.31E-14 7.70E-13
4 ko01200* Carbon metabolism 28/331 94/5400 5.94E-13 2.61E-11
5 ko00640* Propanoate metabolism 9/331 21/5400 1.67E-06 5.88E-05
6 ko00620 Pyruvate metabolism 10/331 28/5400 3.18E-06 9.32E-05
7 ko01210 2-Oxocarboxylic acid metabolism 6/331 13/5400 6.02E-05 0.002
8 ko00010 Glycolysis / Gluconeogenesis 11/331 48/5400 0.000 0.002
9 ko02020 Two-component system 5/331 10/5400 0.000 0.003
10 ko00280* Valine, leucine and isoleucine degradation 9/331 35/5400 0.000 0.003
11 ko00720 Carbon fixation pathways in prokaryotes 5/331 11/5400 0.000 0.005
12 ko04020* Calcium signaling pathway 16/331 105/5400 0.001 0.008
13 ko04922* Glucagon signaling pathway 11/331 59/5400 0.001 0.010
14 ko03010* Ribosome 18/331 133/5400 0.001 0.014
15 ko04261 Adrenergic signaling in cardiomyocytes 14/331 92/5400 0.001 0.015
16 ko00650* Butanoate metabolism 6/331 22/5400 0.002 0.017
17 ko00710 Carbon fixation in photosynthetic organisms 6/331 22/5400 0.002 0.017
18 ko00071* Fatty acid degradation 7/331 30/5400 0.002 0.018
19 ko04022* cGMP - PKG signaling pathway 15/331 108/5400 0.002 0.021
20 ko01230* Biosynthesis of amino acids 10/331 63/5400 0.005 0.040

Note: * also significantly expressed in other organs. Sorted by q-value.