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. 2024 Apr 8;25(4):261–297. doi: 10.2174/0113892029273121240401060228

Table 19.

Top 20 of 34 selective KEGG pathways in the liver.

No. ID Description Significant Annotated p-value q-value
1 ko04610 Complement and coagulation cascades 37/265 55/5400 1.98E-36 2.97E-34
2 ko00140 Steroid hormone biosynthesis 15/265 33/5400 7.31E-12 5.46E-10
3 ko00830 Retinol metabolism 14/265 38/5400 1.12E-09 5.59E-08
4 ko00260* Glycine, serine and threonine metabolism 11/265 29/5400 5.09E-08 1.90E-06
5 ko03320 PPAR signaling pathway 14/265 56/5400 3.03E-07 9.05E-06
6 ko00120 Primary bile acid biosynthesis 6/265 10/5400 2.35E-06 5.85E-05
7 ko04976 Bile secretion 12/265 51/5400 4.34E-06 9.27E-05
8 ko00220 Arginine biosynthesis 6/265 12/5400 9.50E-06 0.000
9 ko00980 Metabolism of xenobiotics by cytochrome P450 9/265 32/5400 1.49E-05 0.000
10 ko01230* Biosynthesis of amino acids 12/265 63/5400 4.30E-05 0.001
11 ko00053 Ascorbate and aldarate metabolism 5/265 10/5400 5.64E-05 0.001
12 ko00982 Drug metabolism - cytochrome P450 8/265 31/5400 8.90E-05 0.001
13 ko00340 Histidine metabolism 6/265 17/5400 0.000 0.001
14 ko01040 Biosynthesis of unsaturated fatty acids 6/265 18/5400 0.000 0.002
15 ko00591 Linoleic acid metabolism 6/265 22/5400 0.001 0.005
16 ko01200* Carbon metabolism 13/265 94/5400 0.001 0.006
17 ko00500 Starch and sucrose metabolism 6/265 24/5400 0.001 0.007
18 ko00983 Drug metabolism - other enzymes 6/265 24/5400 0.001 0.007
19 ko00100 Steroid biosynthesis 4/265 12/5400 0.002 0.016
20 ko00430 Taurine and hypotaurine metabolism 3/265 6/5400 0.002 0.016

Note: * also significantly expressed in other organs. Sorted by q-value.