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. 2024 Apr 8;25(4):261–297. doi: 10.2174/0113892029273121240401060228

Table 2.

Top 20 of 459 genes with description selectively expressed in the brain (Br) based on their abundance (n = 3).

No. Gene Name Product (Description) Last Ref.* Median Organ FPKM p-value q-value Mean/total
Mean Total
1 Dio2 Preoptic regulatory factor 1 [50] Sp 11.5 14.1 5.821E-08 3.324E-07 0.82
2 Scg3 Secretogranin III [51] Du 197.4 215.7 4.057E-09 1.592E-05 0.91
3 Gabbr1 Gamma-aminobutyric acid (GABA) B receptor 1 [52] Ad 448.3 627.1 2.797E-06 2.563E-05 0.71
4 Asic2 Acid-sensing (proton-gated) ion channel 2 [53] Co 19.1 25.8 8.626E-08 9.567E-05 0.74
5 Adcyap1r1 Adenylate cyclase-activating polypeptide 1 receptor type 1 [54] Co 36.9 44.8 1.593E-07 1.165E-04 0.82
6 Chst10 Carbohydrate sulfotransferase 10 [55] He 37.1 47.6 3.197E-06 3.522E-04 0.78
7 Larp6 La ribonucleoprotein domain family, member 6 - St 17.8 24.1 3.871E-06 3.944E-04 0.74
8 Vsnl1 Visinin-like 1 [56] Il 406.5 450.9 1.252E-06 4.572E-04 0.90
9 Snap91 Synaptosomal-associated protein 91 [57] Co 139.3 148.7 1.341E-06 4.692E-04 0.94
10 Tceal3 Transcription elongation factor A (SII)-like 6 [58] He 132.8 141.2 2.179E-06 5.977E-04 0.94
11 Pdzd4 PDZ domain containing 4 [59] Du 42.5 50.0 2.611E-06 6.401E-04 0.85
12 LOC100911402 Cell cycle exit and neuronal differentiation 1 - He 231.8 236.2 3.063E-06 6.991E-04 0.98
13 Acsbg1 Acyl-CoA synthetase bubblegum family member 1 - Lu 106.6 126.1 3.093E-06 7.091E-04 0.85
14 Gdap1l1 Ganglioside-induced differentiation-associated protein 1-like 1 [60] Du 70.6 77.1 3.576E-06 7.453E-04 0.92
15 Adgrb3 Adhesion G protein-coupled receptor B3 [61] Du 22.1 22.8 3.932E-06 7.981E-04 0.97
16 Fam131b Family with sequence similarity 131, member B [62] Lu 56.2 58.1 3.942E-06 8.091E-04 0.97
17 Plp1 Proteolipid protein 1 [63] He 1572.6 1599.8 4.805E-06 8.959E-04 0.98
18 Nipal4 NIPA-like domain containing 4 - Du 6.3 7.9 1.199E-05 9.210E-04 0.79
19 RragB Ras-related GTP-binding protein B-like [64] He 15.2 19.4 2.190E-05 1.143E-03 0.78
20 Stmn3 Stathmin-like 3 [65] Du 887.3 918.2 8.338E-06 1.180E-03 0.97

Note: Sorted by q-value. Ad, adrenal gland; Co, colon; Du, duodenum; He, heart; Il, ileum; Ki, kidney; Lu, lung; Sp, spleen; St, stomach.

* Last Ref. was based on the reports documented in PubMed (www.pubmed.gov) before June 10, 2023.