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. 2024 Apr 8;25(4):261–297. doi: 10.2174/0113892029273121240401060228

Table 20.

Top 20 of 46 Selective KEGG pathways in the lung.

No. ID Description Significant Annotated p-value q-value
1 ko04510 Focal adhesion 45/703 126/5400 4.16E-11 4.01E-09
2 ko04360* Axon guidance 43/703 118/5400 5.36E-11 4.01E-09
3 ko04390 Hippo signaling pathway 40/703 110/5400 2.77E-10 1.38E-08
4 ko04151 PI3K-Akt signaling pathway 59/703 223/5400 2.85E-08 1.06E-06
5 ko04310 Wnt signaling pathway 34/703 100/5400 4.42E-08 1.32E-06
6 ko04550 Signaling pathways regulating pluripotency of stem cells 32/703 93/5400 8.06E-08 2.01E-06
7 ko04668* TNF signaling pathway 29/703 83/5400 2.26E-07 4.83E-06
8 ko04392 Hippo signaling pathway - multiple species 12/703 19/5400 4.56E-07 7.60E-06
9 ko04014* Ras signaling pathway 44/703 159/5400 4.57E-07 7.60E-06
10 ko04010* MAPK signaling pathway 46/703 177/5400 1.76E-06 2.63E-05
11 ko04060* Cytokine-cytokine receptor interaction 43/703 163/5400 2.52E-06 3.41E-05
12 ko04015* Rap1 signaling pathway 37/703 132/5400 2.73E-06 3.41E-05
13 ko04062* Chemokine signaling pathway 35/703 123/5400 3.50E-06 4.03E-05
14 ko04916* Melanogenesis 22/703 63/5400 6.67E-06 7.12E-05
15 ko04340 Hedgehog signaling pathway 13/703 27/5400 9.61E-06 9.57E-05
16 ko04512 ECM-receptor interaction 17/703 46/5400 3.23E-05 0.000
17 ko04341 Hedgehog signaling pathway - Fly 10/703 19/5400 4.01E-05 0.000
18 ko04144* Endocytosis 44/703 189/5400 5.91E-05 0.000
19 ko04650* Natural killer cell mediated cytotoxicity 25/703 86/5400 5.92E-05 0.000
20 ko04810* Regulation of actin cytoskeleton 36/703 149/5400 0.000 0.001

Note: * also significantly expressed in other organs. Sorted by q-value.