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Walker 256 cell transplantation induced mechanical allodynia in rats. (A) The PWT was reduced at day 7 (***P < 0.001 vs Sham group, two-way ANOVA), and persisted for at least 35 d in the ipsilateral hindpaw (**P < 0.01 vs Sham group, n = 8, two-way ANOVA). (B) Photograph of the tumor-injected left hindpaw was showed in the rat after 14 days when inoculation. No effect was seen on the NS-injected left hindpaw.
