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. 2024 Jul 20;10(15):e34991. doi: 10.1016/j.heliyon.2024.e34991

Fig. 7.

Fig. 7

Continuous Metformin treatment reversed the co-expression of TGFβRI and TRPV1 in L4-6 DRG. (A) The schematic diagram showed the timeline of Metformin administration and molecular detection. (B) Immunofluorescence assay showed the co-localization of TGFβRI and TRPV1 in DRG neurons from Sham, BCP and Metformin treatment rats (Bar = 100 μm). (C) The proportion of TGFβRI positive and TRPV1 positive co-labeled cells in DRG neurons from Sham, BCP and Metformin treatment rats (***P < 0.001 vs Sham and Metformin group, n = 5, one-way ANOVA).