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. 2024 Jan 11;34(5):e13237. doi: 10.1111/bpa.13237

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© 2024 The Authors. Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Inflammatory response in the brain tissue surrounding the cyst following anthelmintic treatment. (A) Inflammatory score in rats with neurocysticercosis assessed using Iba‐1 immunohistochemistry and HE staining. IS0, cyst surrounded with minimal infiltration (<25 inflammatory cells/40× field); IS1, moderate to severe infiltration (>25 inflammatory cells/40× field) with scar formation around the cyst; IS2, epithelioid macrophages surrounding the cyst, without granulomas; IS3, granulomatous response and/or identification of multinucleated giant cells in the scar surrounding the cyst. (B) Proportion of inflammatory scores expressed as a percentage for parenchymal cysticerci following anthelmintic treatment. Rats were exposed to albendazole + praziquantel (ABZ), oxfendazole + praziquantel (OXF), or an untreated placebo (UT). (***) p‐value <0.0001.