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. 2024 Jan 11;34(5):e13237. doi: 10.1111/bpa.13237

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© 2024 The Authors. Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Gray and white matter associated changes in neurocysticercosis (NCC) rat model. (A) Top, HE staining on infected brain. Left, cyst surrounded by gray matter showing severe spongy change (arrows) and inflammatory infiltrate (arrowhead); Right, cyst surrounded by white matter showing slight spongy change (arrow), but inflammatory infiltrate (arrowhead). Bottom, neurofilament staining for spheroids on infected brain. Left, cyst surrounded by gray matter showing severe spongy change (arrowhead) and abundant associated spheroids (arrows); Right, cyst surrounded by white matter showing varicosities (arrows) with diameters <10 μm, and slight spongy change (arrowhead). Scale bar = 100 μm. (B) Pathological features in untreated rats within gray and white matter areas. Gray matter is the most affected area in NCC. Percentages are used to express values for spongy change (SC >0) and inflammation (IS >0), while counts for spheroids. Error bars indicate the standard error of the mean. (***) p‐value <0.0001.