Figure 1.

Overview of patient recruitment and patient exclusion. ∗Definition of pathogenicity or variant of unknown significance (VUS) was based on the merger of the 3 following databases. ClinVar (https://www.ncbi.nlm.nih.gov/clinvar (db accessed July 11, 2023); LOVD (https://databases.lovd.nl/shared/variants/HNF1B#object_id=VariantOnTranscript%2CVariantOnGenome&id=HNF1B&order=VariantOnTranscript%2FDNA%2CASC&search_transcriptid=00009498&search_VariantOnTranscript/DNA=c.738G%3ET&page_size=100&page=1 (db accessed July 11, 2023)) and Leipzig_University (https://www.hnf1b.org (db accessed July 11, 2023).²⁶ A variant was marked as pathogenic if in at least 1 database the variant was labelled “pathogenic”. In all other cases a variant was labelled “VUS.”