Skip to main content
. 2024 Jun 12;300(7):107460. doi: 10.1016/j.jbc.2024.107460

Figure 1.

Figure 1

Effect of long-term high-fat diet feeding on body weight and visceral adipose tissue of wild-type and G6PDS188Frats.A, difference in body weight of wild-type (WT) and G6PDS188F rats before and after feeding high-fat diet (HFD) show body weight increased in HFD fed (WT-HFD and G6PDS188F-HFD) groups compared to their respective NC diet fed (WT-NC and G6PDS188F-NC) groups. However, G6PDS188F-HFD rats gained less weight than WT-HFD rats. B and C, two representative micro-CT scans of wild-type and G6PDS188F rats on NC and HFD showed visceral (pink) and subcutaneous (blue) adipose tissue, and summary results showing visceral adipose tissue volume increased in both the genotypes on HFD. D and E, representative images and summary results of visceral adipose cell sizes demonstrate cell size is increased in WT-HFD but not G6PDS188F-HFD rats as compared with the respective controls (NC). N = 5 in panel A–D and individual cells from five different samples. Two-way ANOVA with post hoc Tukey’s multiple comparison tests was used to compare multiple groups. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗∗p < 0.001.