FIG 2.

Forest plot of overall survival across prespecified subgroups of patients with unresectable, pMMR or not MSI-H metastatic colorectal cancer. The Cox proportional hazard model with Efron's method of tie handling was used to assess the magnitude of the treatment difference between arms. CPS, combined positive score; ECOG PS, Eastern Cooperative Oncology Group performance status; HR, hazard ratio; MSI-H, microsatellite instability high; pMMR, mismatch repair proficient; SOC, standard of care.