TABLE A3.
Histopathological Characteristics According to Socioeconomic Status
| Characteristic | Financial Difficulties | Income | Educational Level | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Medium | Low | P | Low (lowest tertile) | Medium | High (highest tertile) | P | Low | Medium | High | P | |
| Histology, No. (%) | .85 | .062 | .38 | |||||||||
| Invasive ca. NST | 560 (79.1) | 964 (76.9) | 2,935 (77.3) | 1,417 (79.4) | 1,385 (77.7) | 1,349 (75.7) | 1,689 (77.5) | 1,682 (78.2) | 1,123 (76.3) | |||
| Invasive lobular ca | 85 (12.0) | 165 (13.2) | 492 (13.0) | 210 (11.8) | 240 (13.5) | 244 (13.7) | 279 (12.8) | 280 (13.0) | 189 (12.8) | |||
| Mixed NST/lobular | 63 (8.9) | 124 (9.9) | 371 (9.8) | 157 (8.8) | 157 (8.8) | 190 (10.7) | 212 (9.7) | 190 (8.8) | 160 (10.9) | |||
| Grade, No. (%) | .18 | .005 | .37 | |||||||||
| 1 | 119 (17.0) | 206 (16.6) | 701 (18.6) | 294 (16.6) | 333 (18.9) | 326 (18.4) | 401 (18.5) | 368 (17.3) | 261 (17.9) | |||
| 2 | 377 (53.8) | 656 (52.8) | 2,032 (53.9) | 907 (51.3) | 943 (53.5) | 972 (54.9) | 1,176 (54.3) | 1,132 (53.1) | 768 (52.6) | |||
| 3 | 205 (29.2) | 380 (30.6) | 1,034 (27.4) | 566 (32.0) | 488 (27.7) | 473 (26.7) | 587 (27.1) | 630 (29.6) | 431 (29.5) | |||
| IHC-defined subtypes, No. (%) | .10 | .062 | .097 | |||||||||
| Hormone receptor+/HER2+ | 77 (10.9) | 156 (12.5) | 373 (9.9) | 201 (11.3) | 184 (10.4) | 183 (10.3) | 215 (9.9) | 230 (10.8) | 169 (11.6) | |||
| Hormone receptor–/HER2+ | 23 (3.3) | 52 (4.2) | 147 (3.9) | 76 (4.3) | 48 (2.7) | 82 (4.6) | 68 (3.1) | 94 (4.4) | 63 (4.3) | |||
| Hormone receptor+/HER2– | 548 (77.7) | 918 (73.6) | 2,921 (77.3) | 1,333 (74.9) | 1,380 (78.0) | 1,351 (76.2) | 1,700 (78.2) | 1,606 (75.1) | 1,106 (75.6) | |||
| Hormone receptor–/HER2– | 57 (8.1) | 122 (9.8) | 337 (8.9) | 169 (9.5) | 158 (8.9) | 158 (8.9) | 192 (8.8) | 208 (9.7) | 125 (8.5) | |||
NOTE. Income refers to tertiles of household income per consumption unit. Financial difficulties defined according to how monthly household resources allowed participants to live: high (with difficulty), medium (adequately but on the limit), or low (financially comfortable). Educational level: high (high school and three or more years of higher education), medium (secondary school ± 2 years of professional training), and low (no education or primary education).
Abbreviations: IHC, immunohistochemistry; HER2, human epidermal growth factor receptor 2; NST, no special type.