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. 2024 Jun 18;42(24):2908–2917. doi: 10.1200/JCO.23.02099

TABLE A4.

Patient Characteristics According to Income

Characterisitic Low (lowest tertile) Medium High (highest tertile) P
No. (%) 1,786 (33.3) 1,786 (33.3) 1,785 (33.3)
Age at diagnosis, median (IQR) 52.5 (45.3-62.3) 55.7 (47.3-63.6) 56.2 (49.3-63.2) <.001
Age at diagnosis, No. (%) <.001
 <40 182 (10.2) 154 (8.6) 87 (4.9)
 40-49 543 (30.4) 452 (25.3) 411 (23.0)
 50-59 503 (28.2) 524 (29.3) 644 (36.1)
 60-69 408 (22.8) 516 (28.9) 516 (28.9)
 ≥70 150 (8.4) 140 (7.8) 127 (7.1)
Menopausal status, No. (%) <.001
 Premenopausal 856 (48.8) 741 (42.2) 671 (38.3)
 Postmenopausal 897 (51.2) 1,017 (57.8) 1,082 (61.7)
Charlson Comorbidity Index, No. (%) <.001
 0 1,314 (79.8) 1,364 (82.7) 1,431 (86.7)
 ≥1 333 (20.2) 285 (17.3) 220 (13.3)
Breast cancer stage, No. (%) <.001
 I 800 (45.2) 899 (50.7) 940 (53.2)
 II 763 (43.1) 712 (40.1) 672 (38.0)
 III 206 (11.6) 163 (9.2) 155 (8.8)
Breast cancer surgery type, No. (%) .002
 None 1 (0.1) 1 (0.1) 0 (0.0)
 Mastectomy 524 (29.4) 427 (23.9) 437 (24.5)
 BCS 1,260 (70.6) 1,356 (76.0) 1,344 (75.5)
Lymph node management, No. (%) <.001
 SNLB only or none 1,056 (59.1) 1,142 (63.9) 1,190 (66.7)
 Axillary dissection or other 730 (40.9) 644 (36.1) 595 (33.3)
Radiotherapy, No. (%) .75
 No 145 (8.1) 133 (7.4) 141 (7.9)
 Yes 1,640 (91.9) 1,653 (92.6) 1,644 (92.1)
Chemotherapy type, No. (%) <.001
 None 739 (41.4) 838 (46.9) 865 (48.5)
 Adjuvant 800 (44.8) 745 (41.7) 704 (39.5)
 Neoadjuvant or both 247 (13.8) 203 (11.4) 215 (12.1)
Endocrine therapy, No. (%) <.001
 TAM ± OFS 549 (30.8) 480 (26.9) 421 (23.6)
 AI ± OFS 693 (38.8) 763 (42.7) 820 (46.0)
 AI + TAM ± OFS 241 (13.5) 239 (13.4) 228 (12.8)
 None or OFS only 301 (16.9) 304 (17.1) 315 (17.7)
Household adjusted income €, median (IQR) 1,237 (884-1,375) 2,013 (1,750-2,250) 3,250 (2,750-4,000) <.001
Educational level, No. (%) <.001
 Low 984 (56.1) 653 (36.9) 285 (16.0)
 Medium 581 (33.1) 740 (41.8) 691 (38.9)
 High 190 (10.8) 376 (21.3) 801 (45.1)
Financial difficulties, No. (%) <.001
 High 510 (29.0) 113 (6.4) 35 (2.0)
 Medium 553 (31.4) 474 (26.7) 137 (7.7)
 Low 697 (39.6) 1,186 (66.9) 1,598 (90.3)

NOTE. Income refers to tertiles of household income per consumption unit. Financial difficulties defined according to how monthly household resources allowed participants to live: high (with difficulty), medium (adequately but on the limit), or low (financially comfortable). Educational level: high (high school and three or more years of higher education), medium (secondary school ± 2 years of professional training), and low (no education or primary education).

Abbreviations: AI, aromatase inhibitor; BCS, breast-conserving surgery; OFS, ovarian function suppression; SNLB, sentinel lymph node biopsy; TAM, tamoxifen.