Fig 5.

Antibody binding and pseudovirus neutralization. (A) Antibody ELISA binding EC50s to RAVV GPΔMuc and neutralization IC50s against MLV-MARV Musoke pseudoviruses calculated from individual plots shown in Fig. S4 and S5. Antibody CM1, CM2, CM11, and CM12 lineage variants are shaded light orange, orange, teal, and cyan, respectively. (B) ELISA binding profiles of antibody CM1 and CM2 lineage variants to recombinant RAVV GPΔMuc. Shown are means of technical duplicates with error bars indicating standard deviation. Results are of representative experiments repeated at least three times. (C) Neutralization of Musoke MLV-MARV pseudoviruses by antibody CM1 and CM2 lineage variants. Shown are means of technical duplicates with error bars indicating standard deviation. Results are of representative experiments repeated at least three times.