Table 2.
Characteristics, baseline complete blood parameters, and inflammatory markers in MDD patients with or without suicide attempts.
| Characteristics | MDD with SA (n = 43) | MDD without SA (n = 96) | P-value |
|---|---|---|---|
| Sex, n (%) | 0.229 | ||
| Male | 16 (37.21) | 26 (27.08) | |
| Female | 27 (62.79) | 70 (72.92) | |
| Age (years) | 0.705 | ||
| Mean ± SD | 20.49 ± 1.47 | 20.40 ± 1.26 | |
| BMI | 0.323 | ||
| Mean ± SD | 23.82 ± 5.57 | 22.69 6.27 | |
| State of depressive episode, n (%) | 0.135 | ||
| First episode | 37 (86.05) | 90 (93.75) | |
| Recurrent depression | 6 (13.95) | 6 (6.25) | |
| Suicide risk score (8Q score), n (%) | < 0.0001* | ||
| No suicide risk (score = 0) | 0 (0.00) | 59 (61.46) | |
| Low suicide risk (score = 1–16) | 22 (51.16) | 34 (35.42) | |
| High suicide risk (score ≥ 17) | 21 (48.84) | 3 (3.12) | |
| WBC count (× 109 cells/L) | 7.90 ± 1.78 | 7.92 ± 2.30 | 0.959 |
| Neutrophil (%) | 61.67 ± 5.96 | 60.06 ± 6.06 | 0.148 |
| Neutrophil count (× 109 cells/L) | 4.89 ± 1.32 | 4.79 ± 1.63 | 0.727 |
| Lymphocyte (%) | 29.95 ± 5.36 | 33.04 ± 5.36 | 0.002* |
| Lymphocyte count (× 109 cells/L) | 2.35 ± 0.63 | 2.58 ± 0.75 | 0.082 |
| Monocyte (%) | 5.98 ± 3.37 | 5.04 ± 2.36 | 0.063 |
| Monocyte count (× 109 cells/L) | 0.46 ± 0.25 | 0.39 ± 0.21 | 0.106 |
| Platelet count (× 109 cells/L) | 282.6 ± 58.12 | 293.7 ± 71.05 | 0.368 |
| NLR | 2.15 ± 0.55 | 1.92 ± 0.78 | 0.090 |
| MLR | 0.21 ± 0.13 | 0.16 ± 0.08 | 0.005* |
| PLR | 126.29 ± 36.17 | 121.21 ± 40.59 | 0.482 |
| SII (109 cells/L) | 603.05 ± 192.85 | 560.49 ± 232.89 | 0.297 |
| SIRI (109 cells/L) | 0.97 ± 0.59 | 0.74 ± 0.45 | 0.012* |
Data are shown as mean ± SD, unless otherwise noted. *P < 0.05.
MDD major depressive disorder, SA had made at least one suicide attempts during the month prior to assessment, n number of patients, BMI body mass index, 8Q score depression scale from the 8Q Scale, WBC white blood cell, NLR neutrophil-to-lymphocyte ratio, MLR monocyte-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, SII systemic immune-inflammatory index, SIRI systemic inflammation response index.