Table 2.

Cognitive performance following 1 week of AME or placebo supplementation^a

Cognitive tests	AME		Placebo		Intervention effectb
	Baseline	After 1 week	Baseline	After 1 week
Attention and Psychomotor Speed
RTI—reaction time (ms)	378 ± 34	374 ± 37	378 ± 38	378 ± 39	– 5 [– 15, 4]; p = 0.253
RTI—movement time (ms)	248 ± 43	239 ± 46	237 ± 42	242 ± 46	– 12 [ – 21,  – 2]; p = 0.019*
Memory
DMS—total correct (%)	93 ± 7	92 ± 8	90 ± 10	91 ± 9	0 [– 3, 3]; p = 0.879
PAL – first-attempt memory score	17 ± 3	18 ± 2	17 ± 1	18 ± 2	0 [– 1, 0]; p = 0.299
PAL—total errors 12 trial	7 ± 9	7 ± 9	6 ± 6	5 ± 7	N/Ad
Executive Function
MTT—incongruency cost (ms)	57 ± 38	47 ± 37	58 ± 45	44 ± 39	N/Ad
MTT—median latency (ms)	533 ± 78	517 ± 74	542 ± 78	514 ± 65	12 [– 3, 28]; p = 0.113
MTT—multitasking costc	85 ± 78	59 ± 40	89 ± 74	69 ± 62	– 8 [– 29, 14]; p = 0.478
MTT—total errors	2 ± 2	3 ± 3	3 ± 3	2 ± 2	1 [0, 2]; p = 0.151
SWM—total errors 12 trial	18 ± 14	17 ± 13	19 ± 14	16 ± 13	2 [– 3, 7]; p = 0.361
SWM—strategy scorec	8 ± 4	8 ± 5	8 ± 5	9 ± 5	0 [– 2, 1]; p = 0.556

DMS delayed matching to samples test, MTT multitasking test, PAL paired associates learning test, RTI reaction time test, SWM spatial working memory test

*Indicates p < 0.05

^aData are presented as means ± SDs

^bAnalysis was performed with a linear mixed model using intervention, period, and sex as fixed factors, and baseline values as covariate

^cLow scores indicate better performance

^dTreatment effects were not analyzed as a significant intervention*sex interaction was observed.