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Association between daily chocolate consumption and risk of cardiovascular disease using a cubic spline model. The solid line denotes the relative risk of cardiovascular disease according to chocolate consumption, and the spline based on four knots selected at the 5th, 25th, 75th, and 95th percentiles of chocolate consumption; dashed lines were used to represent the 95% CIs (Pnon-linearity < 0.001). The analysis included 878,990 participants from 19 cohort studies
