Table 5.
Patterns of first treatment across therapy classes, followed in 12-month blocks after COPD diagnosis
| At the Time of Diagnosis Treated n = 32,981 |
At the End of Year 1 Treated n = 27,141 |
At the End of Year 2 Treated n = 11,865 |
At the End of Year 3 Treated n = 8,275 |
At the End of Year 4 Treated n = 5,906 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients (n) | % Among Treated | Patients (n) | % Among Treated | Patients (n) | % Among Treated | Patients (n) | % Among Treated | Patients (n) | % Among Treated | ||
| Group | LABA Monotherapy | 415 | 1.3 | 416 | 1.5 | 193 | 1.6 | 127 | 1.5 | 66 | 1.1 |
| LAMA Monotherapy | 9,983 | 30.3 | 6,929 | 25.5 | 2,666 | 22.5 | 1,637 | 19.8 | 1,098 | 18.6 | |
| LABA + ICS | 20,459 | 62.0 | 17,287 | 63.7 | 7,164 | 60.4 | 4,864 | 58.8 | 3,475 | 58.8 | |
| LAMA + LABA | 2,123 | 6.4 | 2,473 | 9.1 | 1,719 | 14.5 | 1,360 | 16.4 | 937 | 15.9 | |
| LAMA + LABA + ICS | 1 | 0.0 | 36 | 0.1 | 123 | 1.0 | 287 | 3.5 | 330 | 5.6 | |
| Untreated | 205,177 | 178,036 | 166,171 | 157,896 | 151,990 | ||||||
COPD: chronic obstructive pulmonary disease; ICS: inhaled corticosteroids; LABA: long-acting beta-agonist; LAMA: long-acting muscarinic antagonist