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. 2024 Aug 17;24:395. doi: 10.1186/s12890-024-03194-4

Table 5.

Patterns of first treatment across therapy classes, followed in 12-month blocks after COPD diagnosis

At the Time of Diagnosis
Treated
n = 32,981
At the End of Year 1
Treated
n = 27,141
At the End of Year 2
Treated
n = 11,865
At the End of Year 3
Treated
n = 8,275
At the End of Year 4
Treated
n = 5,906
Patients (n) % Among Treated Patients (n) % Among Treated Patients (n) % Among Treated Patients (n) % Among Treated Patients (n) % Among Treated
Group LABA Monotherapy 415 1.3 416 1.5 193 1.6 127 1.5 66 1.1
LAMA Monotherapy 9,983 30.3 6,929 25.5 2,666 22.5 1,637 19.8 1,098 18.6
LABA + ICS 20,459 62.0 17,287 63.7 7,164 60.4 4,864 58.8 3,475 58.8
LAMA + LABA 2,123 6.4 2,473 9.1 1,719 14.5 1,360 16.4 937 15.9
LAMA + LABA + ICS 1 0.0 36 0.1 123 1.0 287 3.5 330 5.6
Untreated 205,177 178,036 166,171 157,896 151,990

COPD: chronic obstructive pulmonary disease; ICS: inhaled corticosteroids; LABA: long-acting beta-agonist; LAMA: long-acting muscarinic antagonist