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. 2024 Aug 17;24:395. doi: 10.1186/s12890-024-03194-4

Table 6.

Treatment patterns among overall cohort of patients with COPD

Year 1 Year 2 Year 3 Year 4
Patients
(n, Not Unique)
% of Total Cohort % of All Year 1 Claims Patients (n, Not Unique) % of All Year 2 Claims Patients (n, Not Unique) % of All Year 3 Claims Patients (n, Not Unique) % of All Year 4 Claims
Group ICS 39,093 16.4 14.7 34,826 14.5 32,751 13.8 28,977 13.2
LABA Monotherapy 1,218 0.5 0.4 1,035 0.5 1,882 0.7 3,968 1.4
LAMA Monotherapy 23,661 9.9 12.1 19,905 11.8 18,063 11.2 16,295 10.5
LABA + ICS 43,667 18.3 21.4 38,299 21.9 36,230 21.4 33,518 20.5
LAMA + LABA 5,941 2.5 2.4 6,863 3.4 7,759 4.2 7,842 4.6

LABA + LAMA+

ICS

103 0.0 0.0 702 0.2 2,387 1.0 4,022 2.1
Methylxanthine Monotherapy 927 0.4 0.5 833 0.5 714 0.5 614 0.4
PDE Monotherapy 472 0.2 0.3 495 0.3 558 0.3 622 0.4
SABA Monotherapy 91,418 38.4 39.6 75,805 38.6 71,640 38.7 65,606 39.1
SAMA Monotherapy 6,838 2.9 2.4 5,720 2.3 5,324 2.2 4,676 2.0
SAMA + SABA 17,031 7.2 6.1 13,869 6.0 13,705 6.0 12,259 5.8

COPD: chronic obstructive pulmonary disease; ICS: inhaled corticosteroids; LABA: long-acting beta-agonist; LAMA: long-acting muscarinic antagonist; PDE: phosphodiesterase; SABA: short-acting beta-agonist; SAMA: short-acting muscarinic antagonist