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Association analysis of ZNF592 and the C1 module
| Gene | Variants | Total MAC |
Case MAC | Control MAC | Fraction Case | Fraction Control | OR (95% CI) |
SKAT-O | Burden | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| FDR | P | FDR | P | ||||||||
| ZNF592 | 16 | 19 | 8 | 11 | 0.0023 | 0.0018 |
1.08 (1.01–1.16) |
0.044 | 7.60 × 10–6 | 0.041 | 7.30 × 10–06 |
| Module | Variants |
Total MAC |
Case MAC | Control MAC | Fraction Case | Fraction Control |
OR (95% CI) |
Permutation test | P | Permutation test | P |
| C1 | 180 | 234 | 101 | 133 | 0.029 | 0.022 |
1.31 (1.01–1.70) |
0.19 | 0.048 | 0.078 | 0.006 |
