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. 2024 Jul 1;11(8):2112–2122. doi: 10.1002/acn3.52132

Table 3.

Associations of RAS inhibitor use with AD pathology.

RAS inhibitor use Estimate (SE, p‐value)
Global AD score Amyloid burden Tau tangle density
During the study −0.165 (0.100, 0.099) −0.048 (0.170, 0.780) −0.425 (0.184, 0.022)
During last 5 years of life −0.093 (0.097, 0.338) −0.148 (0.164, 0.369) −0.245 (0.180, 0.177)

Each linear regression model with individual AD pathology measure as the outcome has been adjusted for age at death, sex, and diabetes. Bold values denote statistical significance (p < 0.05).