Table 2.

List of NER protein-protein interactions that are missing or need further validation.

Protein	Interacting NER factors	Interaction domain (residues)	Methods	Reference
XPC	XPA *	154–334	PD	[33]
TFIIH	XPG	XPB, XPD, p62, and p44	PD	[82]
	XPF	XPB RPA32: 4–29;	Mut	[77]
XPA	RPA *	RPA70: 153–176 aa	PD, Mut	[52, 83, 84]
RPA	XPG	N/D	co-IP	[85]
	XPF	RPA70	YH	[86]
XPG	TFIIH	N/D	PD	[82]
	RPA	668–747	co-IP	[85]
XPF	TFIIH	N/D	Mut	[77]
	RPA	N/D	YH	[86]

CoIP: Co-Immunoprecipitation; Mut: Site directed/deletion mutagenesis, PD: pull-down assay, YH: Yeast two-hybrid assay.

^*Interaction interfaces not supported by current experimental structures and functional studies