Table 2.
Cognitive and Neuropsychiatric Features
| PPA Variant | STMSa score (n=67) | MMSE score (n=41) | AVLT sum of 5 trials (n=52) | Category Fluency (animals, n=48) | Boston Naming Test (n=53) | Trail Making Test A (seconds, n=56) | NPI-Qb (sum of symptoms, n=48): |
|---|---|---|---|---|---|---|---|
|
Logopenic (n=35) |
23.5 (8) | 22 (5) | 24 (15) | 9 (5) | 5 (4) | 56 (31) | 4 (3) |
|
Agrammatic (n=28) |
34 (3) | 25 (6) | 31 (11) | 11 (4) | 11.5 (3) | 56 (23) | 2 (2) |
|
Semantic (n=18) |
21 (8) | 17 (8) | 21 (9) | 5.5 (3) | 1 (0.7) | 49 (14) | 5 (3) |
| p. value | <0.001 | <0.05 | 0.027 | ns | <0.001 | ns | ns |
| Mean (SD) |
P. values are based on Kruskal-Wallis H test; for NPI subscales, Fisher’s Exact. One unclassifiable-PPA patient was excluded from analyses.
a
Cognition Scores converted to Short Test of Mental Status scores.
b
NPI-Q: presence of each of the following symptoms was considered as 1 point: delusions, hallucination, agitation/aggression, depression/dysphoria, anxiety, elation/euphoria, apathy/indifference, disinhibition, irritability/lability, motor disturbance, nighttime behaviors, changes in appetite/eating.
*
P < 0.05.
STMS: Short Test of Mental Status; MMSE: Mini-Mental State Examination; AVLT: Rey Auditory Verbal Learning Test; NPI-Q: Neuropsychiatric Inventory Questionnaire.