Table 1.
Patient demographics, Baseline Characteristics and ARDS Severity
|
COVID–ARDS N = 6.702 |
CLASSIC–ARDS N = 1.415 |
p | |
|---|---|---|---|
| Demographics | |||
| age, years, median [IQR] | 64.0 [55.0 to 71.0] | 63.0 [50.0 to 74.0] | 0.361 |
| height, cm, median [IQR] | 170.0 [163.0 to 175.0] | 168.0 [160.0 to 175.0] | < 0.001 |
| weight, kg, median [IQR] | 82.0 [74.0 to 95.0] | 74.0 [62.0 to 86.0] | < 0.001 |
| male gender, n/N (%) | 4.655 (69.5) | 859 (60.7) | < 0.001 |
| BMI, kg/m2, median [IQR] | 28.5 [25.6 to 32.4] | 25.8 [22.5 to 30.1] | < 0.001 |
| SOFA score, median [IQR] | 6.0 [4.0 to 8.0] | 10.0 [7.0 to 12.0] | < 0.001 |
| Comorbidities | |||
| heart failure, N (%) | 633 (9.4) | 143 (10.1) | 0.472 |
| COPD, N (%) | 688 (10.3) | 323 (22.8) | < 0.001 |
| diabetes, N (%) | 1.906 (28.4) | 322 (22.8) | < 0.001 |
| chronic kidney disease, N (%) | 402 (6.0) | 140 (9.9) | < 0.001 |
| liver failure, N (%) | 122 (1.8) | 53 (3.7) | < 0.001 |
| active neoplasm, N (%) | 253 (3.8) | 119 (8.4) | < 0.001 |
| ARDS severity categories | < 0.001 | ||
| mild, N (%) | 1.937 (28.9) | 362 (25.6) | |
| moderate, N (%) | 3.477 (51.8) | 673 (47.6) | |
| severe, N (%) | 1.288 (19.2) | 380 (26.9) | |
Abbreviations: ARDS Acute respiratory distress syndrome, IQR Interquartile range, N Number, BMI Body mass Index, SOFA Sequential organ failure assessment, COPD Chronic obstructive pulmonary disease