Table 5. Literature on proton beam radiotherapy in TETs for PORT.
| Authors | Year | N [N of PORT] | Primary | Prescribed dose, median (range) | Efficacy | Toxicity ≥ grade 3 |
|---|---|---|---|---|---|---|
| Vogel et al. (73) | 2016 | 27 [17] | TET | 61.2 CGE (50.4–70.0 CGE) | 3-year OS: 94% | No |
| 3-year regional control: 96% | ||||||
| Parikh et al. (71) | 2016 | 4 [4] | Thymoma | 57.0 CGE (50.4–66.6 CGE) | No death and no recurrences occurred | No |
| Zhu et al. (70) | 2018 | 6 [5] | Thymoma | 60 GyE (54–70 GyE) | 3 patients experienced recurrences (0 local recurrence) | No |
| Mercado et al. (74) | 2019 | 30 [26] | TET | 54 GyE (45–70 GyE) | 5 patients experienced recurrence (1 local recurrence) | No |
| 4 died (3 died of TETs) |
TET, thymic epithelial tumor; PORT, postoperative radiotherapy; CGE, cobalt-gray equivalent; OS, overall survival; GyE, gray equivalent.