Table 3.
CRC risk score decile | Model development cohort: multivariable model |
Internal validation cohort: multivariable model |
External validation cohort: multivariable model |
External validation cohort: updated multivariable model |
||||
---|---|---|---|---|---|---|---|---|
Colo n | CRC n (%)a | Colo n | CRC n (%)a | Colo n | CRC n (%)a | Colo n | CRC n (%)a | |
First | 3571 | 2 (1.8) | 1502 | 2 (4.7) | 4437 | 2 (2.4) | 3900 | 1 (1.2) |
Second | 3891 | 3 (2.6) | 1610 | 1 (2.3) | 4874 | 9 (11.0) | 3950 | 5 (6.1) |
Third | 3534 | 5 (4.4) | 1454 | 0 (0.0) | 3775 | 6 (7.3) | 3885 | 2 (2.4) |
Fourth | 3842 | 6 (5.3) | 1688 | 3 (7.0) | 4144 | 8 (9.8) | 3349 | 3 (3.7) |
Fifth | 3620 | 8 (7.0) | 1606 | 1 (2.2) | 3724 | 7 (8.5) | 3827 | 4 (4.9) |
Sixth | 3740 | 11 (9.6) | 1674 | 5 (11.6) | 4186 | 10 (12.2) | 4376 | 7 (8.5) |
Seventh | 3867 | 11 (9.6) | 1752 | 4 (9.3) | 4002 | 7 (8.5) | 3794 | 13 (15.9) |
Eighth | 3398 | 10 (8.8) | 1470 | 5 (11.6) | 3327 | 16 (19.5) | 3606 | 9 (11.0) |
Ninth | 3989 | 29 (25.0) | 1644 | 6 (14.0) | 3248 | 7 (8.5) | 3870 | 14 (17.1) |
10th | 3542 | 29 (25.0) | 1454 | 16 (37.2) | 2525 | 10 (12.2) | 3685 | 24 (29.3) |
Total | 36,994 | 114 (100) | 15,854 | 43 (100) | 38,242 | 82 (100) | 38,242 | 82 (100) |
Colo, colonoscopy; CRC, colorectal cancer.
Reflects the percent of total CRC, cases in the cohort accounted for in the CRC, risk score decile.