Table 3.
Summary of NOAELs, LOAELs, ED20s, ED50s and ED80s for emetic effects of T-2, HT-2 and emetine in mink
| Toxin (mg/kg BW) |
IP | Oral | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||||
| NOAELA | LOAELB | ED20C | ED50D | ED80E | NOAELA | LOAELB | ED20C | ED50D | ED80E | |
| T-2 | 0.01 | 0.05 | 0.03 | 0.05 | 0.09 | 0.005 | 0.05 | 0.01 | 0.02 | 0.04 |
| HT-2 | 0.01 | 0.05 | 0.03 | 0.05 | 0.09 | 0.005 | 0.05 | 0.01 | 0.02 | 0.04 |
| Emetine | 1 | 2.5 | 1.36 | 1.96 | 2.83 | 0.5 | 1 | 0.58 | 1.03 | 1.85 |
NOAEL = no observed adverse effect level.
LOAEL = lowest observed adverse effect level.
ED20 = Dose causing emesis in 20% of the animals tested.
ED50 = Dose causing emesis in 50% of the animals tested.
ED80 = Dose causing emesis in 80% of the animals tested. ED20, ED50 and ED80 values were determined using a Proc Probit model.