Skip to main content
. Author manuscript; available in PMC: 2024 Aug 19.
Published in final edited form as: Arch Toxicol. 2015 Apr 9;90(4):997–1007. doi: 10.1007/s00204-015-1508-7

Table 3.

Summary of NOAELs, LOAELs, ED20s, ED50s and ED80s for emetic effects of T-2, HT-2 and emetine in mink

Toxin
(mg/kg BW)
IP Oral


NOAELA LOAELB ED20C ED50D ED80E NOAELA LOAELB ED20C ED50D ED80E
T-2 0.01 0.05 0.03 0.05 0.09 0.005 0.05 0.01 0.02 0.04
HT-2 0.01 0.05 0.03 0.05 0.09 0.005 0.05 0.01 0.02 0.04
Emetine 1 2.5 1.36 1.96 2.83 0.5 1 0.58 1.03 1.85
A

NOAEL = no observed adverse effect level.

B

LOAEL = lowest observed adverse effect level.

C

ED20 = Dose causing emesis in 20% of the animals tested.

D

ED50 = Dose causing emesis in 50% of the animals tested.

E

ED80 = Dose causing emesis in 80% of the animals tested. ED20, ED50 and ED80 values were determined using a Proc Probit model.