Table 4.
Summary of previously reported emetic effects of T-2, HT-2 and emetine
| Toxin | Species | Route | NOAEL (mg/kg BW) | LOAEL (mg/kg BW) | Study |
|---|---|---|---|---|---|
| T-2 | Pigeon | sublingual | n.d. | 0.2 | Fairhurst et al., 1987 |
| T-2 | Pigeon | oral | n.d. | 0.72 | Ellison et al., 1973 |
| Pigeon | iv | n.d. | 0.15 | ||
| Dog | iv | n.d. | 0.25 | ||
| T-2 | Cat | oral | n.d. | 0.08 | Lutsky et al., 1981 |
| T-2 | Cat | ip | n.d. | 2 | Borison et al., 1989 |
| Cat | iv | n.d. | 2 | ||
| T-2 | Cat | sc | n.d. | 0.5 | Sato et al., 1975 |
| T-2 | Pig | intra-aortal | n.d. | 1.2 | Beasley et al., 1986 |
| HT-2 | Pigeon | iv | n.d | 0.68 | Ellison et al., 1974 |
| Emetine | Ferret | oral | n.d | 5 | Hasegawa et al., 2002 |
| Emetine | Pigeon | sc | n.d | 20 | Ferrari et al., 1998 |
| Emetine | Pigeon | im | 1 | 5 | Wolff et al., 1995 |
| Emetine | House shrew | sc | n.d | 40 | Ueno et al., 1987 |
| Emetine | Dog | iv | n.d | 3 | Bhargava et al., 1961 |
| Dog | intraventricular | n.d | 0.1 | ||
| Emetine | Dog | oral | n.d. | 1 | Boyd et al., 1964 |
| Emetine | Cat | oral | n.d. | 0.35 | Child et al., 1964 |
| Cat | sc | 1.4 | 2.8 |