Cytotoxicity and antiviral activity of 2-arylimidazoles 4a–c and 6a against the variola virus (VARV, India3a strain) in the Vero cell culture.

No.	CC50, μM (M ± SD, n = 3)	IC50 (VARV), μM (M ± SD, n = 3)	SI (VARV)
4a	142.38 ± 48.45	0.38 ± 0.09	373
4b	174.89 ± 41.94	1.45 ± 0.36	120
4c	46.25 ± 8.63	0.18 ± 0.03	257
6a	1154.34 ± 272.41	3.96 ± 0.22	291
Cidofovir	1111.5 ± 163.44	43.15 ± 5.48	26
NIOCH-14	1193.4 ± 228.68	0.008 ± 0.003	149 175