| (B) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Agents | IC50 (μM) | |||||||
| KBV1 + NC siRNA | KBV1 + Pgp siRNA | KB31 + NC siRNA | KB31 + Pgp siRNA | DMS-53 + NC siRNA | DMS-53 + Pgp siRNA | HCT-15 + NC siRNA | HCT-15 + Pgp siRNA | |
| DOX | 55.01 ± 2.96 | 2.43 ± 0.15**** | 5.75 ± 0.66 | 5.48 ± 0.95 | 38.47 ± 5.30 | 2.57 ± 0.32*** | 58.29 ± 6.50 | 31.25 ± 4.15** |
| Dp44mT | 1.57 ± 0.66 | 8.34 ± 2.04** | >25 | >25 | 5.44 ± 0.80 | 19.37 ± 0.59**** | 5.49 ± 2.33 | 14.83 ± 2.44** |
| DpC | 2.45 ± 0.68 | 19.01 ± 5.69** | >25 | >25 | 5.57 ± 0.28 | 8.99 ± 0.88** | 4.90 ± 0.29 | 9.14 ± 0.27*** |
| AOBP | 2.79 ± 0.34 | 18.98 ± 5.62** | >25 | >25 | 22.87 ± 1.05 | >25 | 12.56 ± 1.17 | 21.42 ± 2.41** |
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