Non-Native Site-Selective Enzyme Catalysis

. Author manuscript; available in PMC: 2024 Aug 19.

Published in final edited form as: Chem Rev. 2023 Jul 31;123(16):10381–10431. doi: 10.1021/acs.chemrev.3c00215

Scheme 55. (A) Percent of Product Pool in the Synthesis of the Arylomycin Core by P450 MG-AR Variant;369 (B) Intermolecular Cross-Coupling of Nonidentical Monomers by KtnC;370 (C) Reactions of 7-Demethylsiderin (347) with Enzymes KtnC and DesC371.