Table 2.

Model test statistics for the relationship between the hippocampus volume and pain sensitivity.

Term name	t	df	P
Left normalized hippocampus	3.02	14.4	0.009
Right normalized hippocampus	−0.5	17.4	0.65
MPS laterality	−0.54	13.6	0.6
Medication	−2.02	11.9	0.07
Seizure laterality (bilateral)	−0.25	12.6	0.81
Seizure laterality (unilateral)	2.02	11.9	0.07
Left normalized hippocampus × MPS laterality	−0.043	13.5	0.97
Right normalized hippocampus × MPS laterality	0.24	13.7	0.81

A linear mixed model of the relationship between the hippocampus volume and mechanical pain sensitivity rating, with factors such as the number of anti-seizure medications, mechanical pain sensitivity laterality (coded for the left and right forearm), and seizure laterality (bilateral seizure onset for bilateral vs right coded as [0,−1] and unilateral seizure onset for left vs right coded as [1,−1]).

Significance was set at P < 0.05.

MPS, mechanical pain sensitivity.