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. 2024 Aug 13;10(3):e004201. doi: 10.1136/rmdopen-2024-004201

Table 2. Laboratory results.

PedSjDn=19 Diagnostic adSjDn=32 PedSjD versus diagnostic adSjDP value Trial adSjDn=42 PedSjD versus trial adSjDP value
IgG value, median (IQR), g/L 16.1 (13.7–20.0)* 16.6 (12.1–19.7) 0.82 17.9 (13.2–23.5) 0.39
IgG elevated, n (%) 11 (64.7)* 17 (53.1) 0.44 27 (64.3) 0.98
RF-IgM value, median (IQR), IU/mL 18 (1.7–73) 23 (4–65)* 0.67 23 (11.8–58.3) 0.52
RF+ (>5 IU/mL), n (%) 12 (63.2) 23 (74.2)* 0.41 35 (83.3) 0.08
Anti-SSA+, n (%) 13 (68.4) 31 (96.9) 0.004 36 (85.7) 0.12
Anti-SSB+, n (%) 9 (47.4) 15 (46.9) 0.97 22 (52.4) 0.72
CRP>5, n (%), mg/L 2 (10.5) 9 (28.1) 0.18 7 (16.7) 0.71
ESR>15, n (%), mm/hour 6 (31.6) 22 (68.8) 0.010 28 (66.7) 0.011
C3<0.9, n (%), g/L 0 (0) 2 (6.5)* 0.52 6 (14.3) 0.16
C4<0.1, n (%), g/L 1 (5.3)* 0 (0)* 0.38 2 (4.8) 1.00
ANA+, n (%) 16 (88.9) 29 (90.6) 1.00 29 (85.3) 1.00

Significant p values are italicised and bold.

*

Missing data: 0–5.

IgG value elevated for age-related normal range.

adSjDadult-onset Sjögren’s diseaseANAantinuclear antibodiesC3complement 3C4complement 4CRPC reactive proteinESRerythrocyte sedimentation rateIgGimmunoglobulin GPedSjDpaediatric-onset Sjögren’s diseaseRFrheumatoid factorSSASjögren’s syndrome-related antigen ASSBSjögren’s syndrome-related antigen B