Table 3.
Standardised incidence ratios (SIR) for any metachronous second malignant neoplasm (SMN) diagnosed in Finland between 1992-2021 by follow-up interval and age at first primary cancer (FPC).
| Follow-up interval | Age at FPC | Men | Women | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Observed SMNs | Expected SMNs | PYRS | SIR | 95% CI | Observed SMNs | Expected SMNs | PYRS | SIR | 95% CI | ||
| 0.5–5 years | 20–39 | 80 | 24.72 | 37,884.73 | 3.24 | 2.58-4.00 | 175 | 75.25 | 59,420.39 | 2.33 | 2.00-2.69 |
| > 5 years | 20–39 | 287 | 136.07 | 71,663.84 | 2.11 | 1.87-2.36 | 603 | 407.64 | 118,404.86 | 1.48 | 1.36-1.60 |
| All | 20–39 | 367 | 160.79 | 109,548.57 | 2.28 | 2.06-2.52 | 778 | 482.89 | 177,825.25 | 1.61 | 1.50-1.73 |
| 0.5–5 years | 40–59 | 1,606 | 1,064.65 | 185,783.99 | 1.51 | 1.44-1.58 | 2107 | 1,932.10 | 329,456.25 | 1.09 | 1.04-1.14 |
| > 5 years | 40–59 | 4,355 | 3,469.12 | 267,609.15 | 1.26 | 1.22-1.29 | 6075 | 5,871.76 | 603,382.19 | 1.03 | 1.01-1.06 |
| All | 40–59 | 5,961 | 4,533.76 | 453,393.14 | 1.31 | 1.28-1.35 | 8182 | 7,803.87 | 932,838.44 | 1.05 | 1.03-1.07 |
| 0.5–5 years | 60–79 | 11,258 | 11,818.31 | 528,047.72 | 0.95 | 0.94-0.97 | 5868 | 5,569.95 | 439,822.52 | 1.05 | 1.03-1.08 |
| > 5 years | 60–79 | 12,558 | 13,319.69 | 465,984.22 | 0.94 | 0.93-0.96 | 8409 | 7,644.52 | 483,755.58 | 1.10 | 1.08-1.12 |
| All | 60–79 | 23,816 | 25,138.00 | 994,031.93 | 0.95 | 0.94-0.96 | 14277 | 13,214.47 | 923,578.10 | 1.08 | 1.06-1.10 |
| 0.5–5 years | 80+ | 2,949 | 3,312.96 | 92,387.55 | 0.89 | 0.86-0.92 | 2169 | 2,101.83 | 109,319.59 | 1.03 | 0.99-1.08 |
| > 5 years | 80+ | 1,003 | 1,097.98 | 30,237.46 | 0.91 | 0.86-0.97 | 962 | 916.30 | 44,628.81 | 1.05 | 0.98-1.12 |
| All | 80+ | 3,952 | 4,410.94 | 122,625.00 | 0.90 | 0.87-0.92 | 3131 | 3,018.13 | 153,948.41 | 1.04 | 1.00-1.07 |
| 0.5–5 years | All | 15,893 | 16,220.63 | 844,104.99 | 0.98 | 0.96-1.00 | 10319 | 9,679.14 | 938,018.75 | 1.07 | 1.05-1.09 |
| > 5 years | All | 18,203 | 18,022.86 | 835,494.67 | 1.01 | 1.00-1.02 | 16049 | 14,840.22 | 1,250,171.45 | 1.08 | 1.06-1.10 |
| All | All | 34,096 | 34,243.49 | 1,679,598.65 | 1.00 | 0.99-1.01 | 26368 | 24,519.36 | 2,188,190.20 | 1.08 | 1.06-1.09 |
CI: confidence interval; Exp: expected; FPC: first primary cancer; Obs: observed; PYRS: person-years at risk; SIR: standardised incidence ratio; SMN: second malignant neoplasm.