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. 2024 Aug 2;28(4):474. doi: 10.3892/ol.2024.14607

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Copyright: © 2024 Chang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — CANX is highly expressed in liver cancer and is associated with the survival of patients with liver cancer. (A) Box plot shows the expression of CANX in 369 liver cancer tissues and 160 normal tissues in the integrated The Cancer Genome Atlas and Genotype-Tissue Expression project data. (B) cBioPortal was used to assess the association between CANX and hepatocellular carcinoma survival. (C) Effect of CANX overexpression and siRNA in HuH-7 cells. (D) CANX siRNA efficiency in HuH-7 cells demonstrated by western blotting. (E) CANX overexpression efficiency in HuH-7 cells demonstrated by western blotting. (F) Effect of CANX overexpression and siRNA in Li-7 cells. (G) CANX siRNA efficiency in Li-7 cells demonstrated by western blotting. (H) CANX overexpression efficiency in Li-7 cells demonstrated by western blotting. The relative protein expression level was semi-quantified using Image J software. *P<0.05; ***P<0.001. ns, not significant; CANX, calnexin; T, tumor; N, normal; LIHC, liver hepatocellular carcinoma; siRNA, small interfering RNA; NC, negative control.