Fig 9. MCPyV T antigens have opposing effects on the transcription of type I IFN response genes.
Heat map of selected genes involved in type I IFN signaling differentially regulated in nHDFs overexpressing MCPyV T-Ags (LT, sT, LTtr), either individually or in combination, compared to the respective lentiviral vector controls. Values are derived from the RNA-Seq analysis that was performed once in donor I and once in donor II. The color code refers to the log2FCs and n.s. is denoted for genes with a padj. value >0.05.