Figure 2.

Sequence similarities among Stx phages found in the 71 O145:H28 strains. A dendrogram based on the Mash distance matrix of 83 Stx phage genomes is shown in the left panel, along with their stx genotypes, integration sites, and phage clusters, which were defined based on the pairwise Mash distance with a cutoff distance of 0.05. The phage indicated by attB_in_PPompW/yecE was the duplicated L-Stx2a phages that were integrated into the attB_in_PPompW and yecE loci in strain 112648. These duplicated phages were treated as one phage. The tree in the right panel is the same ML tree of O145:H28 strains shown in Figure 1. Stx phages were connected to their host strains by lines colored according to the phage clusters. Strain Ech14022 and its S-Stx2a phage are indicated by asterisks.