Table 2.

Changes in FACT-G scores from baseline to weeks 6, 12, and 24 and the last assessment before death.

Outcome	Week	Mean change, active group	Mean change, control group	Difference (95% CI)	p Value
FACT-G	6	3.6	−1.5	5.2 (−0.1 to 10.5)	0.216
	12	5.9	−0.9	6.7 (0.2 to 13.3)	0.172
	24	10.8	−2.2	13 (5.7 to 20.2)	0.004
	Last	−6.7	−9.7	3 (−4 to 9.9)	1.000
HADS A	6	−1.3	−0.5	−0.9 (−2.1 to 0.4)	0.728
	12	−0.7	−0.9	0.2 (−1.1 to 1.5)	1.000
	24	−1.4	−1.1	−0.3 (−2.6 to 1.9)	1.000
	Last	0.5	−0.3	0.8 (−1.1 to 2.7)	1.000
HADS D	6	−0.3	0.2	−0.5 (−1.5 to 0.6)	1.000
	12	−0.3	0.3	−0.6 (−1.8 to 0.6)	1.000
	24	−0.8	0.4	−1.2 (−2.6 to 0.3)	0.472
	Last	2.0	0.7	1.4 (−0.4 to 3.2)	0.520

FACT-G scores at weeks 6, 12, and 24 and the last assessment before death were compared to baseline and between the two study groups using a paired t test. The Bonferroni correction was used for each outcome to adjust the p values for multiple comparisons, and so the values in this table are already multiplied by four. The last assessment before death was made a median of 4.1 weeks (range 0.4–6.7 weeks) before death.