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. 2024 Aug 19;14:19138. doi: 10.1038/s41598-024-69726-4

Table 1.

Participant characteristics.

ALL Q1 Q2 Q3 Q4 P-value
Range of olfactory score 0–6 0–1 2 3–4 5–6
Number of samples 1444 428 245 469 302
Age, years 63.4 ± 9.8 68.4 ± 8.6 64.5 ± 9.1 61.5 ± 9.4 58.2 ± 8.9  < 0.001
Men, n (%) 521 (36.1) 195 (45.6) 111 (45.3) 137 (29.2) 78 (25.8)  < 0.001
Education, years 13.5 ± 1.8 13.3 ± 1.9 13.5 ± 1.8 13.6 ± 1.7 13.6 ± 1.7 0.010
Smoking ever, n (%) 542 (37.5) 165 (38.6) 105 (42.9) 156 (33.3) 116 (38.4) 0.355
MoCA-J score 25.6 ± 2.6 24.7 ± 2.7 25.5 ± 2.5 26.1 ± 2.5 26.4 ± 2.2  < 0.001
ICV-normalised GMV for brain (× 10−3) 402.9 ± 35.6 390.3 ± 34.9 399.6 ± 35.7 407.6 ± 34.2 416.0 ± 32.9  < 0.001

Continuous data are presented as mean ± standard deviation. Categorical data are presented as number (percentage). The olfactory score is the total score for spearmint and stuffy socks. The MoCA-J is the Japanese version of the Montreal Cognitive Assessment. The ICV-normalised GMV represents the ratio of grey matter volume to intracranial volume. P-values were derived using the Jonckheere–Terpstra and Cochran–Armitage tests for trends in the distributions of continuous and categorical variables, respectively.