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. 2024 May 21;23:811–815. doi: 10.17179/excli2024-7170

Current biological and pharmacological updates on Tinospora cordifolia

Shubham Kumar 1, Murtaza M Tambuwala 2, Yachana Mishra 3,*, Vijay Mishra 1
PMCID: PMC11333724  PMID: 39165586



Guduchi, scientifically known as Tinospora cordifolia, is one of the non-controversial and extensively used herbs in Ayurvedic medicine belonging to the family Menispermaceae (Sharma, 2017[17]). In the Ayurvedic healthcare system, guduchi is considered precious for its curative properties. The plant's numerous chemical contents, which are dispersed throughout its various plant sections, and each has unique medicinal properties, are responsible for its pharmacological actions. Glycosides, diterpenoid lactones, sesquiterpenoids, steroids, phenolic and aliphatic substances, essential oils, multiple kinds of fatty acids, polysaccharides, and tinosporaside (Figure 1(Fig. 1)) are among these chemical components (Ninama et al., 2022[9]). Only a few systematic reviews have been published highlighting the possible advantages of the plant, however, the majority of preclinical and clinical evidence demonstrated the wound healing, diabetes, hepatic, anti-toxic, anti-stress, inflammatory, and additional bioactive properties of T. cordifolia. As there is a scarcity of studies reflecting the therapeutic role of T. cordifolia, the present letter highlights the beneficial effects of T. cordifolia in the treatment of different diseases. Additionally, it gives researchers a direction for future research and suggests ways to improve the safety and effectiveness of T. cordifolia in treating a variety of diseases and other uses (Table 1(Tab. 1); References in Table 1: Ambalavanan et al., 2021[1]; Balkrishna et al., 2023[2]; Bhandari et al., 2022[3]; Gupta et al., 2018[4]; Kamboj et al., 2023[5]; Kumar et al., 2022[6]; Maya et al., 2022[7]; Mishra et al., 2023[8]; Philip et al., 2018[10]; Prakash Kumar et al., 2011[11]; Prasad and Chauhan, 2019[12]; Pushp et. al., 2013[13]; Salve et al., 2015[14]; Sarkar et al., 2023[15]; Sharma et al., 2019[16]; Singh et al., 2020[18]; Tiwari et al., 2014[19]; Yow et al., 2023[20]).

Figure 1. (A) Plant part of T. Cordifolia and (B) Chemical structure of Tinosporaside.

Figure 1

Table 1. An update on the biological and pharmacological activities of Tinospora cordifolia.

Table 1

Declaration

Funding

None.

Conflict of interest

The authors declare no conflict of interest.

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