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. 2023 Sep 12;22(12):2059–2078. doi: 10.2174/1570159X21666230912101441

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© 2024 The Author(s). Published by Bentham Science Publishers

© 2024 The Author(s). Published by Bentham Science Publishers. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode.

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Fig. (3) — Effects of THC:CBD edible formulation on single-unit activity of pyramidal neurons recorded in PFC and DAergic neurons in the VTA of non-stressed vs. stressed male (A-F) and female (G-L) rats. (A, G) Representative histology example of electrode placement in PFC. (B, H) Firing rate of pyramidal neurons. (C, I) Percentage of spikes per burst of pyramidal neurons. (D, J) Representative histology example of electrode placement in VTA. (E, K) Firing rate of DAergic neurons. (F, L) Percentage of spikes per burst of DAergic neurons. Data bars correspond to mean ± SEM, two-way ANOVA, Holm-Sidak post-hoc unpaired; *p < 0.05; **p < 0.01; ***p < 0.001; **** p < 0.0001.