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Effects of THC:CBD edible formulation on expression of Akt (A, G), GSK3 α/β (B, H), mTOR (C, I), BDNF (D, J), D1-R (E, K) and D2-R (F, L) in PFC of non-stressed and stressed male (A-F) and female (G-L) rats. Representative Western blots (Bottom) and quantification (Top) in the PFC of comparison between non-stressed and stressed cohorts. Data correspond to mean ± SEM, two-way ANOVA, Holm-Sidak post-hoc unpaired; *p < 0.05; **p < 0.01; ***p < 0.001.
