Table 3.

Distribution of haplotypes of IL-10 gene SNPs between CRC, colon cancer, rectum cancer cases, and HS.

Haplotype IL-10 1082–592	CRC cases		Colon cancer cases		Rectum cancer cases		HS		P1	OR1 (95%CI)	P2	OR2(95%CI)	P3	OR3(95%CI)
	N = 260	Frequency	N = 138	Frequency	N = 122	Frequency	N = 330	Frequency
Hap1 (A1082C592) vs. others	95	0.364	59	0.430	34	0.277	100	0.303	0.11	1.32 (0.94–1.86)	0.01	1.72 (1.15–2.60)	0.61	0.89 (0.56–1.39)
Hap2 (A1082A592) vs. others	67	0.259	34	0.244	35	0.290	100	0.303	0.22	0.80 (0.55–1.14)	0.22	0.75 (0.48–1.19)	0.74	0.93 (0.58–1.44)
Hap3 (G1082C592) vs. others	77	0.298	31	0.222	48	0.396	120	0.364	0.08	0.74 (0.52–1.04)	0.003	0.51 (0.32–0.80)	0.56	1.14 (0.74–1.73)

HS: healthy subjects. N: Number. OR: odds ratio. 95%CI: confidence interval.

P-values are estimated by the chi-square test or the Fisher's exact test when appropriate.

P1 and OR1= CRC cases vs. HS, P2 and OR2= Colon cancer cases vs. HS, P3 and OR3= Rectum cancer cases vs. HS.

Significant P-values are represented in Bold.