Fig. 11.

Quantitative cytotoxicity assessment as measured by the percentage of live SKOV3 cells following incubation with culture medium alone for 24 h (positive control), culture medium containing free BrCy112 for 3 and 24 h, culture medium containing BrCy112-nEGs for 3 and 24 h, and methanol for 24 h (negative control). Error bars represent standard deviations. Triple asterisks indicate statistically significant differences between the positive control and free BrCy112 and between positive and negative controls with $p<0.001$. There were no statistically significant differences in the mean fraction of live cells incubated with the cell culture medium without any other agents or the cell culture medium containing BrCy112-nEGs.