Fig. 7. Visual representation of molecular interactions within the VEGFR-2 active site. The 3D model showcases the binding patterns of the investigated 4 (in pink), 11 (in yellow), 20 (in cyan), and the reference compound SRB (in green). Each compound exhibits unique conformational orientations and interactions within the kinase domain, highlighting their potential differential impacts on VEGFR-2's enzymatic activity and signaling pathways (PDB: 3wze). This visual representation offers valuable insights into the compounds' molecular mechanisms and potential effects on VEGFR-2 and its associated signaling pathways.