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. 2022 Mar 6;67(5):245–256. doi: 10.17221/14/2021-VETMED

Table 1. Blood biochemical analyses and enzyme activities in the rat serum.

Assays Units Control STZ STZ/IN-1 STZ/IN-2
ALT μkat/l 0.81 ± 0.37 2.14 ± 0.53* 1.31 ± 0.44 (1.72 ± 0.51) 1.07 ± 0.38** (1.20 ± 0.35)
AST μkat/l 1.93 ± 0.70 6.32 ± 1.30* 3.75 ± 0.94** (4.24 ± 0.98) 2.96 ± 0.86** (3.47 ± 0.88**)
TG mg/l 1 338 ± 215 2 899 ± 434* 2 048 ± 389 (2 295 ± 406) 1 897 ± 402** (1 718 ± 314**)
Ketones mmol/l 242 ± 58 1 224 ± 297* 661 ± 183** (890 ± 208) 504 ± 157** (774 ± 181)
Albumin g/l 43 ± 5 39 ± 3 ND ND
Glucose g/l 1 060 ± 320 4 780 ± 1 120* 4 420 ± 950* (ND) 4 530 ± 1 040* (ND)

One μkat corresponds to the amount of ALT or AST required to generate 1.0 μmole of pyruvate or glutamate per minute at 37°C, respectively

STZ/IN-1 and STZ/IN-2 represent one (1.0 ml at 196 mg/ml) and two consecutive infusions of albumin, respectively

*< 0.05 compared with that of control; **P < 0.05 compared with that of STZ

ND = not determined; STZ = streptozotocin; TG = triglycerides