Table 1.
Inclusion criteria | Reporting on pathogens causing fever in human (inpatients or outpatients) |
---|---|
Studies conducted in the targeted geographical areas | |
Abstract and full text available in English or Chinese | |
Samples tested from normally sterile sites1 | |
Samples analysed in a laboratory setting | |
Total number of individuals tested is clearly stated for population-based studies (case reports and case series were categorised separately and did not need to meet this criterion) |
|
Exclusion criteria | Published before 1980 |
Primary focus on malaria, HIV, or tuberculosis | |
Non-clinical studies (descriptions of laboratory methods, modelling studies, economic evaluations, opinion pieces) | |
Drug or vaccine trial | |
Studies conducted in travellers | |
Other studies of disease not including laboratory identification of pathogens causing fever |
1The definition of a confirmed diagnosis was restricted to pathogens detected in or cultured from samples from normally sterile sites (e.g. bacterial or fungal isolates cultured from the blood, cerebrospinal fluid, arthrocentesis or paracentesis fluid, etc., or virus or parasite detection in the blood or cerebrospinal fluid) or serological evidence of current or past infection