Skip to main content
. 2024 Jun 5;9(7):890–902. doi: 10.1016/j.jacbts.2024.04.006

Figure 2.

Figure 2

TPHi Attenuates Pulmonary Arterial Hypertension in the SuHx Rat Model: Noninvasive Echocardiographic Measurements

(A) Representative pulsed-wave Doppler images for pulmonary artery acceleration time (PAAT) measurement in the 3 groups at the end of the study. The SuHx group has a mid-systolic notch, which is no longer present in the group treated with TPHi. (B to G) PAAT as a surrogate of mean pulmonary arterial pressure and pulmonary vascular resistance, RV end-diastolic diameter (RVEDD) and end-diastolic anterior wall thickness (RVAWD), left ventricular end-diastolic diameter (LVEDD) and end-diastolic posterior wall thickness (LVPWD), and heart rate (HR). Mean ± SEM, n = 7-14, ANOVA–Bonferroni post hoc test. ∗∗P < 0.01; ∗∗∗P < 0.001.